Senior Director, Solid Tumor Asset Lead, Translational Development

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Bristol Myers Squibb has pioneered the development of immuno-oncology therapies and continues to diversify in drug development for the treatment of cancers. Our world-class Translational Development organization is exploring new aspects of tumor and immune biology to create tailored, individualized treatment strategies that will offer the greatest possible benefit to patients. We are looking for experienced translational scientists to help drive improved understanding of disease biology, mechanism of action, and predictive biomarkers in our late-stage clinical oncology portfolio. Ideal candidates will possess a strong scientific background, effective communication skills, and experience working in a matrixed industrial environment.

Position Summary 

The Asset Lead role will be responsible for development and execution of translational strategies in solid tumor oncology for assigned programs. Key responsibilities of this role are to act as a lead scientist to implement and generate and deliver on innovative biomarker strategies for clinical programs including patient selection, differentiation, resistance, combinations and indication selection.  The Asset Lead will develop reports and publications on translational data generated to support asset development and contribute to regulatory submissions. This individual will work on cross-functional project teams to drive execution of translational/biomarker plans working with disease and lab scientists, as well as BMS members from clinical, medical, commercial, regulatory, and diagnostics. Individual will also engage with external academic collaborators/Key Opinion Leaders (KOLs).

 

Key Responsibilities:

• Integrate translational research and clinical development, developing biomarker strategies in alignment with clinical development objectives, leading efforts for data generation and interpretation and for communication to the development teams.

• Responsible for understanding external research environment, partnering with other functions both internally and externally to coordinate the execution of Translational development deliverables.

• Engages functional groups to develop, champion, implement and align biomarker strategies for development projects in support of the overall R&D portfolio goals.

• Effectively engages with teams and matrix leadership to define, revise and progress translational biomarker plans.

• Continually analyzes progress, engages in critical thinking, and asserts strong problem-solving towards delivering key data and interpretations essential for decision making.

• Delivers high quality biomarker strategies for understanding mechanism of action/resistance, target engagement, pharmacodynamics endpoints and patient selection.

• Ensures the output of the biomarker plans meets established project standards.

• Engages team members to ensure alignment of biomarker strategies with clinical operational plans and with functional area capabilities to execute and deliver on robust translational biomarker data package to support trial and program

• Builds productive relationships with team members that interact with the translational clinical biomarker group.

• Effectively interfaces with functional areas to ensure strategic alignment and to identify resources needed to deliver on biomarker goals.

• Communicates key biomarker program information, risks, and milestones, and manages information flow across team members

 

Qualifications & Experience:

• Ph.D. in Oncology/Hematology or related field with 12+ years of industry experience including significant time in translational capacity

• Requires comprehensive knowledge of principles, concepts and / or methodologies within drug discovery or clinical development

• Has significant understanding of the role of translational research/medicine and clinical biomarkers in drug development

• Demonstrated knowledge of oncology and/or tumor-immunology disease biology

• Preferably has strong understanding of modality agnostic therapies including small molecules and biologics

• In-depth understanding of solid tumor oncology with knowledge of current and evolving clinical landscape and competitive scenarios, with therapeutic area experience a plus

• Strong scientific background with demonstrated impact using clinical, translational, and mechanistic data

• In depth understanding of early or late-stage drug and translational development process with proven track record of successful implementation of biomarker strategy

• Clinical protocol authoring and review of regulatory documents

• Working knowledge of technological platforms covering biomarker measures including but not limited to genomics, gene expression, immune profiling, and flow cytometry.

• Excellent data analysis and problem-solving skills

• Exceptional verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, scientific presentations and regulatory submissions (INDs/NDAs) with ability to synthesize complex scientific concepts into simple communication points

• Proven track record of writing and publishing scientific articles as major scientific contributor

• Proven scientific/project leadership expertise and experience working on complex global teams, managing people/projects as well as leading external collaborations

• Experience interacting with health authorities

• Ability to influence internal and external stakeholders across the business continuum

#LI-Hybrid

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Brisbane - CA - US: $272,720 - $330,476
Cambridge Crossing: $272,720 - $330,476 
Madison - Giralda - NJ - US: $243,500 - $295,064
Princeton - NJ - US: $243,500 - $295,064 
San Diego - CA - US: $262,980 - $318,672


The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. 

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
 

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

​Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.

R1601801 : Senior Director, Solid Tumor Asset Lead, Translational Development