At Alexion, AstraZeneca Rare Disease, we are innovators, leaders, and collaborators. At the heart of everything we do is an intense desire to pursue the toughest challenges and truly change the world for people living with rare and
devastating diseases.
The Global Marketing & Market Access team is a fully integrated commercial strategy team, aligning global marketing, global value & access, and commercial excellence across all therapeutic and disease areas. This team’s purpose is to partner with both global colleagues (R&D, Operations, Corporate Affairs, Finance, et al) and regional and local Commercial colleagues to ensure the successful development and launch of innovative therapies that will deliver value for all our stakeholders. Our unique culture is centered on collaboration, authenticity, creativity and pushing the boundaries on everything we do to advance patient care.
The Portfolio Analytics Lead conducts robust portfolio forecasting and reporting capabilities to define financial opportunities across indications/therapeutic areas for the pipeline which aid in enterprise-wide portfolio decision making. This position will support assessment of internal and external opportunities, including rationale, technical and commercial considerations, in partnership with key organization stakeholders. As such, the ideal candidate is highly collaborative and confident interfacing with senior and middle management (Global Program Leaders and team members, regional Commercial management, and Therapeutic Area management and team members) on internal governance interactions.
The key focus of this role is to provide financial and analytical support and oversight and produce long-term topline and patient forecasting to enable data-driven decision making (integrated with market insights), demand and infrastructure planning, and deeper comprehension of underlying commercial opportunities. This work will include the development of strategic business cases, scenarios, and inputs into portfolio prioritization.
This position is based in Boston.
You will be responsible for:
- Lead revenue forecasting across all early commercial pipeline indications and business development opportunities:
- Lead annual processes related to portfolio assessment, long-term planning, management, and prioritization for Alexion portfolio, including analyzing changes with respect to prior evaluations.
- Facilitate cross-functional discussions at program and portfolio level to influence program level strategic and forecasting discussions, provide portfolio view and cross-product knowledge, and generate alignment on company long-term strategic plans.
- Serve as a strategic partner to Head of Early Commercial Strategy; incorporate business intelligence to develop, align and present key assessments to support executive level strategic decisions for new opportunities and business development.
- Integrate insights from functional expertise spanning epidemiology, market research, competitive intelligence, market access, and others.
- Act as a thought leader for the Portfolio Analytics team, supporting the Portfolio Analytics Head to set standards, guidelines, processes, and systems and coaching the broader team and partners accordingly
- Demonstrate high-scientific aptitude across multiple therapeutic areas, and the ability to integrate such thinking into business deliverables
- Deliver content/results/findings at all levels, including Executive Leadership, of a global, matrixed organization
- Develop and use models for scenario planning with a variety of decision frameworks, draw insight from these models, and present and explain them to stakeholders.
- Collaborate closely with Finance to project long range financials, valuation and capital needs; provide Finance with all necessary revenue inputs for their consolidation, analysis and management reporting of long- and mid-term planning.
- Ensure data integrity and provide ad-hoc and standard reports and presentations to management; identify variations from prior strategic plans and operational planning; provide information around potential consequences and recommendations for corrective actions.
- Maintain relevant knowledge of external market landscape, pipeline, and competition in core therapeutic areas.
- Drive optimization and continuous improvement of strategic portfolio and commercial processes, systems, and operational excellence.
You will need to have:
- Bachelor Degree in Business/Finance, MBA preferred; is a strong plus
- At least 10 years’ experience, with a history in one or more of the following areas: strategic planning, corporate development/business development, business analytics, market research, finance/controlling or management consulting
- Previous experience in leading processes spanning long term business planning, portfolio analytics and portfolio prioritization supporting Business Unit/Regional Unit P&L analysis, including detailed sales forecasting, cost analysis and project economic evaluation
- Exceptional quantitative and analytical modeling skills with an ability to translate complex business questions into financial models
- The ability to manipulate heavy sets of data, including building and updating discounted cash flow and technical probability assessment
- Mastery of Excel and modeling software
- Ability to think strategically about current portfolio and future evolution in the context of competition and external trends
- Strong analytical and operational capability, with ability to manage projects and timelines; effective stakeholder management skills
- Strong written and verbal communication skills; ability to produce high-quality, impressive deliverables that are suitable for senior executive audience
- Highly collaborative, strong interpersonal skills and cross-functional team experience; ability to lead and influence within a matrix
- Willingness to travel (domestic, international) ~ 10% of the time, in accordance with company policies
- The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.
We would prefer for you to have:
- At least 5 years of experience in the biopharmaceutical industry
- Experience analyzing and developing economic proposals for external innovation, including licensing and acquisition opportunities.
- Scientific background is a plus.
- Direct experience performing a similar role in-house or in consulting.
Date Posted
22-Jul-2026
Closing Date
06-Aug-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.