UPLIZNA Portfolio Marketing, Senior Manager

Career Category

Marketing

Job Description

UPLIZNA Portfolio Marketing, Senior Manager

This leader will partner across Marketing, Sales, Market Access, Medical, Patient Services, Analytics, Sales Operations, Training, Digital Field Enablement, and other cross-functional teams to translate strategic priorities into high-impact execution. The role requires strong strategic thinking, operational discipline, cross-functional influence, and the ability to connect portfolio-level strategy with field-ready tools, account-based execution, and measurable business outcomes.

Success in this role requires a portfolio mindset, strong collaboration skills, analytical rigor, and a bias for simplifying complex business opportunities into clear, actionable plans.

UPLIZNA is a monoclonal antibody targeting the CD19 cell surface marker on B-cells and is building strong momentum as a multi-indication autoimmune franchise. UPLIZNA is approved in multiple rare autoimmune diseases and is entering a pivotal phase of growth, with significant opportunity to expand patient impact across neurology, immunology, rheumatology and gastroenterology.

With multiple indications, UPLIZNA requires an integrated portfolio approach to strategy, planning, and execution. The UPLIZNA Portfolio Marketing Senior Manager will play a critical role in shaping the long-term commercial strategy for the franchise, driving brand planning excellence, advancing the Phases of Growth roadmap, and building scalable marketing capabilities that strengthen execution across indications.

Responsibilities

Developing and Evolving Strategy

• Drive the evolution and execution of the UPLIZNA Phases of Growth strategy, including the 12-quarter roadmap.

• Lead and support the annual UPLIZNA brand planning process across the portfolio, ensuring strategic priorities, behavioral objectives, tactical plans, KPIs, and investment choices are clearly aligned across indications.

• Translate portfolio strategy into clear, actionable commercial priorities that accelerates and optimizes growth across the franchise.

Account Management

• Build and lead the account management marketing strategy for UPLIZNA, including tools, resources, and engagement approaches that support strategic account planning, IDN engagement, matrix coordination, and local pull-through.

• Develop portfolio-level marketing resources and field enablement tools that clarify roles, responsibilities, desired outcomes, and timing across matrix teams supporting demand generation, patient starts, access navigation, and adherence.

• Support the optimization of customer engagement across the portfolio by identifying opportunities to improve targeting, segmentation, omnichannel coordination, field execution, and account-level impact.

Veeva Suggestions and Technology

• Lead the portfolio approach and strategy for Veeva Suggestions, including business objectives, trigger strategy, message alignment, governance, field feedback loops, and performance measurement.

• Identify opportunities to leverage AI, modular content, omnichannel engagement, and scalable execution models to improve efficiency, consistency, and impact across the UPLIZNA portfolio.

• Support portfolio KPI tracking, dashboards, and measurement plans to help leadership assess progress, identify risks, and adjust execution as needed.

Cross-Functional Collaboration

• Partner across Marketing, Market Access, Patient Services, Case Management, Site of Care, Sales, Training, Analytics, and field leadership to align priorities, accelerate key growth opportunities, and improve the customer and patient experience.

• Collaborate with indication marketing leads to ensure UPLIZNA messaging, resources, field tools, and portfolio positioning are consistent where appropriate while supporting indication-specific needs.

• Embody Amgen Values and help foster a collaborative, high-performing culture across the UPLIZNA brand team and cross-functional partners.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The marketing professional we seek is a collaborator with these qualifications.

Basic Qualifications

• Doctorate degree and 2 years of portfolio strategy, marketing, or account management experience OR

• Master’s degree and 4 years of portfolio strategy, marketing, or account management experience OR

• Bachelor’s degree and 6 years of portfolio strategy, marketing, or account management experience OR

• Associate’s degree and 10 years of portfolio strategy, marketing, or account management experience OR

• High school diploma / GED and 12 years of portfolio strategy, marketing, or account management experience

Preferred Qualifications

• Strong marketing and commercial strategy competencies, including brand planning, marketplace analysis, insight generation, segmentation, strategic prioritization, tactical planning, and multichannel engagement.

• Experience translating complex business strategies into clear, actionable, field-ready plans.

• Experience leading cross-functional initiatives and influencing teams without direct authority.

• Strong analytical skills, with the ability to interpret business performance, customer insights, field feedback, and KPI data to inform strategic decisions.

• Experience developing or managing field enablement tools, account-based marketing resources, CRM/Veeva suggestions, alerts, dashboards, or omnichannel engagement strategies preferred.

• Rare disease, specialty, neurology, immunology, or multi-indication brand experience preferred.

• Launch, growth brand, or portfolio strategy experience preferred.

• Experience collaborating with Sales, Market Access, Medical, Patient Services, Analytics, Sales Operations, Training, and Legal/Regulatory/Compliance partners.

• Strong communication skills with the ability to engage, connect, and influence senior management as well as sales and marketing organizations.

• Ability to manage multiple projects, vendors, workstreams, and cross-functional stakeholders simultaneously.

• Ability to simplify ambiguity, create structure, and drive execution in a fast-moving, matrixed environment.

• Strong attention to detail, sound judgment, and commitment to compliant execution.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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Salary Range

149,349.25USD -202,060.75 USD