Sr. Director, Materials Science

Job Description

Senior Director, Materials Science

Job Description:

At our company, we are driven by a shared purpose—to invent for life. The Senior Director of Materials Science plays a critical role in advancing that mission. This leader is responsible for providing strategic and technical leadership for materials characterization methodologies, phase screening platforms, and extraneous matter investigations to enable deep understanding of drug substances and drug products and successful advancement of small molecules, biologics, and vaccines from discovery through development and commercial launch.

Reporting to the Associate Vice President of Analytical Enabling Capabilities, the Senior Director will lead a , multidisciplinary team of 30-35 talented people managers, scientists, and technical experts at our Rahway, NJ site. In this role, you will partner closely with leaders across Discovery, Preclinical Development, Manufacturing, Quality, and Regulatory to ensure our science delivers with excellence across the development continuum. Your focus will be on building modality agnostic scientific excellence in materials science across drug substance and drug product and developing fungible expertise that can flex with our company's evolving portfolio.

This is a unique opportunity to influence the future of our pipeline, champion scientific excellence in domain of materials characterization, and build a high‑performing organization that will power the next generation of therapies for patients around the world.

Key Responsibilities

1. Scientific Excellence & Innovation Leadership

• Set a forward‑looking strategy for materials science that anticipates the needs of an evolving pipeline and emerging modalities.
• Ensure the delivery of scientifically sound data, insights, and methods that enable decisive scientific and regulatory advancement.
• Foster a culture of scientific curiosity and innovation, encouraging teams to explore novel analytical technologies and workflows that accelerate deep product understanding and development.

2. Quality, Integrity & Regulatory Excellence

• Uphold the highest standards of quality and data integrity, ensuring our analytical approaches meet global regulatory expectations.
• Lead the delivery of robust CMC content for IND/CTA/NDA submissions and partner with regulatory colleagues to confidently address health authority inquiries.

3. Operational Excellence & Compliance Culture

• Champion a strong compliance mindset and ensure systems, processes, and teams operate consistently with cGMP/GLPs (as needed), SOPs, good documentation practices, safety standards, and corporate expectations.
• Drive operational excellence by simplifying workflows, eliminating barriers, and enabling teams to work with speed, clarity, and purpose.

4. Strategic Partnership & Enterprise Leadership

• Build strong, trusting relationships with partners across discovery, development, and manufacturing to align priorities, support program needs, and deliver on mission‑critical timelines.
• Promote transparency, collaboration, and a shared sense of ownership for pipeline success.

5. Building & Developing a High‑Performing Organization

• Inspire, empower, and develop a team, ensuring people have the resources, skills, and support needed to excel.
• Set clear expectations, elevate performance standards, and build a culture where continuous learning, accountability, and inclusion thrive.
• Recruit and nurture talent to ensure the organization is equipped for future scientific challenges and opportunities.

6. Communication & Leadership Presence

• Communicate strategy, priorities, and scientific outcomes with clarity and authenticity to senior leaders, collaborators, and teams.
• Promote a culture of open dialogue, shared learning, and partnership across all levels.

Qualifications:

Education: 

• PhD in relevant scientific discipline with 10+ years’ experience; MS in relevant scientific discipline with 12+ years’ experience

Required:

• 10 + years of development experience
• 6 + years of direct leadership experience
• Must have experience in drug substance and/or drug product development
• Technical expertise in physical and/or materials characterization
• Demonstrated ability in leading multi-disciplinary teams and mentoring and developing talent. 
• Excellent interpersonal, communication, and collaboration skills with proven ability to drive alignment with a set of stakeholders.
• Strength in delivering results on firm deadlines in support of drug development.

Preferred:

• Breadth of experience from discovery through commercial launch

Required Skills:

Analytical Method Development, Analytical Thinking, Cross-Cultural Teams, Data Integrity, Drug Development, Materials Engineering, Materials Science, Materials Technology, Molecular Structure, Multidisciplinary Teamwork, Operational Excellence, Organizational Compliance, People Leadership, Technical Leadership

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$173,200.00 - $272,600.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

Domestic/International

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Not Applicable

Shift:

1st - Day

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

08/7/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.