Location
San Diego, CA
Compensation
$124k–$186k USD
Market range · function + seniority
p25 · target · p75 · n=800
Posted $186k · in the market band
Tailor your résumé to this role in 30 seconds.
Free account · ATS keyword check · per-job bullet rewrite by Claude.
Job Description
We are seeking a senior, hands‑on Senior Automation Engineer to help define, evolve, and execute the technical vision for laboratory automation platforms. This role combines platform ownership and architectural leadership with deep, practical involvement in instrument integration, troubleshooting, and live lab operations.
The ideal candidate has shaped automation platforms or workcell architectures that scale across instruments, workflows, and teams, while remaining close to the lab and accountable for reliability in production. You translate long‑term vision into pragmatic systems that scientists and operators trust. This is an onsite position in San Diego.
Primary Stack: .NET (C#), JavaScript, Relational Databases
Key Responsibilities:
Automation Platform Vision & Ownership
Hands‑On Integration & Operational Support
Reliability, Usability & Operator Experience
Data & Informatics Integration
Technical Leadership
What Success Looks Like
Education and Experience:
#LI-KM1
#LI-Onsite
Pay Range:
$124,000 - $186,000Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
On-Site DesignatedFlex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Onsite
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
More open roles at Vertex Pharmaceuticals
Hiring velocity, headcount trend, and every open posting on one page.
Open postings ranked by description similarity — useful if this role isn't quite right.