Global Clinical Development Medical Director- Vaccines/Oncology

Introduction to role:

Are you a clinical research physician ready for new opportunities? Would you like to play a pivotal role in the development of potential medicines? If you are passionate about being a medical leader for a cross-functional team in a group that drives action towards the improvement of global public health– join us! As a Global Clinical Development Medical Director you will have an outstanding opportunity to further elevate the Infectious Disease unit in one of the world’s most respected biopharmaceutical companies. The role holds a great development opportunity for the successful candidate whilst contributing to the positive journey that AstraZeneca is on. 

Accountabilities: 

• Providing medical and scientific leadership in the global development of new medicines targeted at indications in the field of vaccines 

• Help invent, implement, and interpret clinical trials in one or more development programs (Phase 1 through Phase 3) 

• Build positive relationships with a network of external scientific specialists and opinion leaders as well as site investigators 

• Work closely with colleagues in other internal functions including Patient Safety, Biometrics, Regulatory Affairs, Clinical Operations, and Translational Medicine 

• Medical oversight to ensure the safety of study participants including review of Adverse Events of Special Interest and Serious Adverse Events and review and writing of safety narrative reports 

• Medical oversight responsibilities for medical activities outsourced to third party vendors 

• Provide authoritative medical input and writing of regulatory documents and interactions/responses with regulatory authorities 

• Provide authoritative medical and scientific analysis and interpretation of data from ongoing studies and in the literature 

• Prepare publications and presentations for scientific meetings and congresses 

Essential Skills/Experience: 

• Fully qualified physician (MD or MD PhD) with clinical experience in oncology  

• Demonstrated clinical research expertise in oncology 

• At least 3 years of pharmaceutical industry knowledge and experience 

• Strong understanding of clinical trials methodology with experience in the design, execution, and interpretation of clinical studies (e.g., medical monitoring, data cleaning, clinical study report writing) 

• Excellent teamwork and cross-functional collaboration skills 

• Ability to communicate effectively in clinical team settings 

• Excellent verbal and written communication skills (including giving presentations) in English 

• Demonstrated AI/digital mentality and experience applying AI-enabled and generative AI tools to support clinical development activities (e.g., data analysis, medical writing, clinical trial operational efficiency) 

• Must demonstrate high integrity 

• Be office based at the Gaithersburg AstraZeneca site at least 3 days a week 

Desirable Skills/Experience: 

• Clinical experience in vaccines and/or monoclonal antibodies 

• Named Investigator on several clinical trials 

• Progressed medicines into first time in human Phase 1, Phase 2 delivery of proof of principle, and/or Phase 3 pivotal efficacy studies 

• Experience with Translational programs moving from preclinical to first in human studies and interpretation of immunological assay results 

• Significant and consistent peer-reviewed publication track record 

• Have organized and delivered Advisory Boards with international Key External Experts 

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. Join us in our unique and ambitious world. 

The annual base pay for this position ranges from $249,827 to $374,741. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

Why AstraZeneca? 

We are a changemaker on the world stage at an exciting frontier of medicine. This is backed by deep knowledge and experience in our field. Building on this, we lead the way into the future with energy and drive. We are helping to transform healthcare and build pandemic preparedness to protect against future health crises and to bring lasting immunity to people around the globe. We are committed to our central role in addressing pandemic and endemic diseases and ensuring our products continue to reach and benefit millions of people around the world. 

Date Posted

16-Jul-2026

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.