Manager, US Business Finance

Job Title: Manager, US Business Finance

Location: Boston, MA

Introduction to role:
Are you ready to turn GTN analytics and finance business partnering into sharper decisions that protect revenue integrity and fuel growth? This role puts you at the heart of the US Commercial Business for a transformative therapy area, where precise financial insight directly supports access for patients who need it most. Based in Boston, you will connect planning, analytics, and strategy to drive better decisions at speed.

As Manager, US Business Finance, you will be the strategic finance partner to Commercial leaders—owning planning cycles, translating performance into action, and shaping investment choices. You will blend deep FP&A expertise with specialized Gross-to-Net analytics, reconciling SAP actuals with Anaplan plans and turning advanced analysis in Excel and Power BI into clear, executive-ready recommendations. Do you thrive at the intersection of Market Access, pricing, and finance, where your analysis influences how we invest and compete?

You will collaborate across US Finance, Market Access, Sales Operations, Accounting, and our shared services team in Costa Rica. With ethics and transparency as your compass, you will improve processes end-to-end—enhancing forecasting accuracy, strengthening controls, and introducing smarter models, including machine learning, to sharpen GTN insights.

Accountabilities:
Financial Planning and Forecasting: Lead annual budgeting, quarterly forecasts, and long-range planning for the US Commercial Business. Prepare in-depth analysis of GTN, expense budgets (MTP/RBU), forecasts, and actuals; identify risks, opportunities, and resource optimization needs. Maintain accounts and cost centers in full compliance with Group reporting requirements and drive continuous improvements in planning and reporting.

Operating Expense Management: Build cost consciousness across the organization and lead targeted cost-savings initiatives without sacrificing commercial effectiveness. Monitor spend trends, surface risks and opportunities, and guide resource allocation to enhance ROI. Run monthly expense performance reviews with Commercial collaborators and convert results into clear actions.

Strategic Business Partnership: Serve as the lead finance partner to US Commercial Leadership for investment support and financial guidance. Partner closely with leaders supporting Market Access to enable data-driven decisions on programs and contracting. Evaluate the financial impact of pricing strategies, payer agreements, and market access initiatives on net revenue and ROI.

Analytics, Reporting and Insights: Produce and synthesize performance reporting using advanced Excel, Power BI, and other platforms, translating complex data into actionable insights for senior leadership. Build executive-level presentations that communicate performance, trends, and recommendations. Quantify key drivers—volume, price, mix, and cost—and support GTN analytics including SAP-to-Anaplan reconciliations, materiality reviews, and month-end close.

Cross-Functional Collaboration: Liaise with Global Finance Services in Costa Rica to deliver shared priorities. Align assumptions and embed insights through collaboration with Market Access, Contracting, Brand, Sales Operations, and Accounting. Partner with US Market Access teams to understand payer dynamics and contracting changes, assessing impacts on GTN liabilities and commercial investments. Maintain rigorous compliance with financial controls, audits, and SOX.

Process Improvement and Best Practices: Identify, design, and implement improvements to planning and reporting that enhance accuracy and efficiency. Promote standardization and procedures across finance processes, systems, and analytics. Advance continuous improvement in GTN processes, data models, and reporting frameworks, including the adoption of machine learning and AI. Early success looks like establishing a credible GTN baseline and cadence for reviews; over time, your insights will shape pricing, contracting, and investment strategies at scale.

Essential Skills/Experience:
- B.S. Degree in Finance or Accounting
- 5+ years of financial experience; pharmaceutical industry experience preferred
- Demonstrated finance business partnering experience with ability to influence and advise commercial partners.
- Knowledge of the US pharmaceutical operating model
- Strong FP&A background with experience in budgeting, forecasting, and variance analysis
- Proficiency in SAP, Excel (advanced functions including Power Query), and PowerPoint
- Strong analytical ability to synthesize complex financial data into clear, actionable insights
- Exceptional communication and interpersonal skills with ability to present to and challenge senior leadership
- High degree of accuracy with attention to detail
- Ability to manage multiple priorities with ownership and urgency in a fast-paced, collaborative environment

Desirable Skills/Experience:
- Experience with Anaplan, Hyperion Planning, Power BI, or other advanced analytics platforms
- Familiarity with GTN analytics, revenue accounting, or Market Access
- Understanding of revenue recognition standards (IFRS 15/ASC 606)
- CPA qualification or progress toward certification

The annual base pay for this position ranges from $94,736.80 to $142,105.20. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:
Join a high-performing finance community that blends sharp commercial judgment with a deep sense of purpose. We bring diverse experts together to spark bold thinking, harness advanced technology, and turn data into decisions that accelerate life-changing medicines to patients. You will be trusted to do the right thing, with ethics and transparency at the center of how we operate, and supported to grow your impact as you modernize planning, improve GTN analytics, and influence strategy across the enterprise. We value kindness alongside ambition, pairing pace and accountability with a collaborative, learning mindset—so your contribution scales from weekly decisions to long-term outcomes for patients.

Call to Action:
Own the finance narrative for a critical US business and turn your insights into measurable impact—take the next step in your career with us today!

Date Posted

09-Jul-2026

Closing Date

26-Jul-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.