Manufacturing Associate III/IV

Posting Title – Manufacturing Associate III / IV – Cell Culture (Days) 

About This Role  

Our factories run 24/7 operations. Our manufacturing teams work 12-hour shifts (either Days or Nights) on a 2-2-3 calendar rotation. 

• Shift Details: This role follows a 2-2-3 calendar rotation on days (6:00 AM – 6:00 PM ET) 

• Internal Shift Details: Red Days rotating schedule 

Our Manufacturing Associates perform processing steps and manufacturing support activities in our Drug Substance facility in Research Triangle Park (RTP). These teams are the backbone of our operations – each playing a critical role in delivering our therapies to the patients who need them. 

Our teams are organized by the steps in the biomanufacturing process that they operate in; including – Upstream (Cell Culture), Downstream (Purification), and Media & Solution Preparation. Manufacturing Associates perform these critical steps in a clean environment governed by Current Good Manufacturing Practices (cGMP). 

This role’s primary focus is on Upstream Cell Culture operations. 

What You’ll Do  

• Perform inoculation thaws, splits, and pools using aseptic technique with WAVE bags and ITV cans 

• Prepare bioreactors by executing automated CIP/SIP recipes using DeltaV 

• Standardize and calibrate pH and DO probes during bioreactor preparation 

• Perform inoculation of bioreactors across multiple scales 

• Support cell growth operations, including media feeds and process additions 

• Conduct routine sampling and in-process testing to monitor product quality 

• Standardize and maintain laboratory and manufacturing equipment, including: 

• Vi-Cell Blu/XR 

• Osmometer 

• pH meters 

• RapidPoint BGA 

• Conductivity meters 

• Biosafety cabinets 

• Small-scale centrifuges 

• Accurately document activities in accordance with cGMP and SOP requirements 

• Maintain a clean, safe, and compliant manufacturing environment 

• Collaborate cross-functionally with Manufacturing, MSAT, Quality, and Engineering teams 

Who You Are  

You’re driven by a mission to save lives and bring a deep sense of purpose to the work you do. Biomanufacturing is complex, and you thrive in fast-paced environments where learning agility, problem-solving, and adaptability are essential. 

Required Skills for a Manufacturing Associate III: $25.96 - $34.13 Pay Range 

• The following combination of academic and/or relevant experience may be considered: 

• Bachelor’s degree from an accredited college or university, STEM preferred and at minimum .5 years of direct experience 

• A BioWorks Certificate or associate's degree, STEM preferred and at minimum 1 year of direct experience 

• A High School Diploma (or equivalent) and at minimum of 1.5 years of direct experience 

• Previous experience in a cGMP environment 

• Ability to follow SOPs and work effectively on shift schedules if required 

• Demonstrated documentation and data integrity skills 

• Knowledge of aseptic technique and cleanroom practices 

• Exposure to Delta V, Syncade, or similar systems 

• Experience performing bioreactor preparation, inoculation, and monitoring is preferred 

• Hands-on experience with mammalian cell culture operations is preferred 

Required Skills for a Manufacturing Associate IV: $31.25 - $40.87 Pay Range 

• The following combination of academic and/or relevant experience may be considered: 

• Bachelor’s degree from an accredited college or university, STEM preferred and at minimum 2 years of direct experience 

• A BioWorks Certificate or associate's degree, STEM preferred and at minimum 2.5 year of direct experience 

• A High School Diploma (or equivalent) and at minimum of 3 years of direct experience 

• Previous experience in a cGMP environment 

• Ability to follow SOPs and work effectively on shift schedules if required 

• Demonstrated documentation and data integrity skills 

• Knowledge of aseptic technique and cleanroom practices 

• Exposure to Delta V, Syncade, or similar systems 

• Experience performing bioreactor preparation, inoculation, and monitoring 

• Hands-on experience with mammalian cell culture operations