In vivo biologist-Immunology

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

At Lilly Corporate Center in Indianapolis, the in vivo immunology group contributes to the advancement of the immunology portfolio by creating innovative in vivo models to interrogate complex biology. Our collaborative efforts span across both discovery and development organizations, working closely with scientists specializing in immunology, bioengineering, chemistry, biomolecule formulation and developability, genetic medicines, and other related disciplines to drive immunology research and therapeutic development. We seek an in vivo scientist who will lead research studies focused on understanding immunological mechanisms using advanced in vivo models to enable drug discovery efforts. The ideal candidate will demonstrate expertise in commonly used immunology models, as well as the ability to develop and implement new models relevant to immunological diseases. Responsibilities include model development and execution, analyzing data, and collaborating with multidisciplinary teams to advance therapeutic development. Strong experience with, in vivo assay development and implementation, and interpretation of preclinical data is essential. Strong interpersonal skills and the ability to excel in a highly collaborative environment are vital.

Responsibilities:

• Provide strong scientific and technical leadership to establish and innovate in in vivo models to interrogate mechanisms and pathways relevant to the discovery of novel treatments for autoimmune diseases and related pathologies.
• Be hands-on in the laboratory to leverage and develop in vivo and in vitro systems to generate critical data supporting new and existing programs.
• Function independently, work within a team-oriented lab environment and communicate results to cross functional discipline teams.
• Provide supervision and mentoring to 1-2 scientists, performance evaluations, and career development.
• Requirement for accurate record keeping, independent data analysis, and reporting of data in written and oral formats.
• Will perform work in full compliance with Lilly Research Policies and complete all required training activities in the timeframe specified.

Basic Qualifications/Requirements:

• Ph.D. in related field physiology, immunology, biology, pharmacology, or a closely related field Strong/extensive in vivo capabilities, or master's with 8+years of experience.

Additional Skills/Preferences:

• Experience working with humanized mouse models such as the NSG.
• Experience of chronic non resolving fibrosis models Understanding of in vivo models related to immune aging in aged mice Proficient in cell isolation, cell culture, and immune cell differentiation procedures Knowledgeable with ex vivo sample assays and analyses (e.g. ELISA, RNA isolation, Nanostring)
• Familiarity with FACS and immunophenotyping Ability to prioritize activities across multiple projects independently and effectively while demonstrating initiative and appropriate risk taking. Excellent communication and organizational skills are required to present findings in internal and external forums.

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Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$126,000 - $204,600

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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