Process Development Engineer

Synthego is enabling genome engineering at scale with a blend of scientific instrumentation, industrial automation, and data science. Our team of scientists and engineers are putting multidisciplinary fields together to solve problems that no one field can tackle alone. 

  We are searching for a motivated and enthusiastic individual to join our Chemistry Development team to improve our oligonucleotide manufacturing process and to directly contribute to launching new oligonucleotide products. As a Process Development Engineer at Synthego, you will have direct responsibility for the development of new techniques for synthesis and purification of RNA and DNA from nanomole to millimole scales. Primary goals include scaling manufacturing processes, improving cost and margin, improving quality of oligonucleotide products, and reducing production times. This role will include developing in both a research and clinical environment, as well as transferring technology into the manufacturing lines. With a focus on the successful introduction and adoption of new technologies in operations, this role will collaborate closely with the hardware, software, operations, quality, and product teams. 

BS in Chemistry, Chemical Engineering, Bio-engineering or a similar field 

2-5 years of industry experience within a research/manufacturing/production environment, preferably in a small company/start-up setting 

Direct experience in the synthesis and analysis of oligonucleotide products 

Experience in data analysis with languages such as Python, SQL.  

Understanding of aseptic handling techniques, including liquid handling, pipetting, reagent preparation, and consumables. 

Experience using larger scale instrumentation such as HPLCs, oligonucleotide or peptide synthesizers, tangential flow filtration, and/or liquid handlers. 

Strong desire to work in a fast-paced, collaborative start-up environment 

Demonstrates strong interpersonal and communication skills (both written and oral) 

Demonstrates ability to work independently and as part of a team to curate and execute development projects. 

Deep knowledge of oligonucleotide chemistry or reagent manufacturing, specifically using fluorophores, quenchers, or other oligonucleotide modifiers 

Familiar with qPCR 

Familiar with fluorescence assays and how to create functional tests for newly developed products 

Familiar with biotechnical instrumentation in aspects such as coding new methods, data analysis pipeline, servicing, etc 

Medical, dental, and vision benefits 

401k Program 

Catered meals on Tuesday and Thursday 

Paid parental leave 

Flexible paid time off 

Education Reimbursement Program 

Synthego is a pioneering force in the biotechnology industry, dedicated to advancing the frontiers of CRISPR cell and gene therapies through cutting-edge CRISPR technology and expertise. Our mission is to provide unparalleled access to best-in-class CRISPR solutions at scale, empowering agility in life science research and development from discovery through clinical trials. From streamlined approaches to licensing through full technical and regulatory support from our industry-leading experts, Synthego is enabling greater access to CRISPR technology driving to improved outcomes in patient therapeutic treatments.